Naltrexone decreases self-injurious behavior.

نویسندگان

  • B H Herman
  • M K Hammock
  • A Arthur-Smith
  • J Egan
  • I Chatoor
  • A Werner
  • N Zelnik
چکیده

The effect of naltrexone (0.5, 1.0, 1.5, and 2.0 mg/kg) on the frequency of self-injurious behavior (SIB) was investigated in three male adolescents. The frequency of total SIB was reduced significantly in all three subjects; dose-dependent decreases (at 0.5, 1.0, and 1.5 mg/kg) in SIB frequency were observed in the two mentally retarded subjects. These data suggest a role for opioid peptides in SIB.

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عنوان ژورنال:
  • Annals of neurology

دوره 22 4  شماره 

صفحات  -

تاریخ انتشار 1987